A new saline-immersion technique shows promise for complex colorectal resections.

• 181 lesions treated with an en bloc approach achieved an R0 resection rate of 92.3%.
• Overall, 4.4% of patients experienced adverse events, with only four needing further intervention.

This technique enhances the safety profile of endoscopic procedures, supporting wider use in Western surgical practice.

• 93.4% of procedures were performed under conscious sedation, making it a viable option for patient comfort.