Predicting Liver Failure After Hepatectomy: Key Early Indicators

Early liver function tests can help surgeons identify patients at risk for post-hepatectomy liver failure (PHLF), improving outcomes.

  • In a study of 445 patients, 8.5% developed PHLF.
  • On postoperative day 3, bilirubin ≥1.8 mg/dl (sensitivity 93.3%) and INR ≥1.18 (sensitivity 80.6%) strongly predicted PHLF.
  • Relying on current guidelines starting at day 5 could delay important interventions.

Early recognition of liver dysfunction could enhance surgical decision-making and patient outcomes.

Journal Article by Abdelhadi S, El-Ahmar M (…) Sandra-Petrescu F et 7 al. in Front Surg

© 2025 Abdelhadi, El-Ahmar, Vedder, Halawa, Orth, Hermann, Mönnichs, Vassilev, Reissfelder and Sandra-Petrescu.

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