The MELD score predicts postoperative complications in acute appendicitis, aiding surgical decision-making.

• Analyzing 121,207 patients, 30-day mortality was just 0.5% (567 cases).
• MELD 3.0 significantly outperformed previous versions in predicting outcomes, with a risk cutoff of 11 indicating higher complication rates.

This score enhances patient selection and risk assessment for appendectomy, whether laparoscopic or open.

• Postoperative sepsis occurred in 5.8% of cases, underscoring the importance of effective risk stratification.