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TOP STITCHES

  • Biomarkers for Recurrent Rectal Cancer Outcomes
    Identifying molecular biomarkers could enhance patient selection for salvage surgery in locally recurrent rectal cancer, impacting surgical strategies and patient outcomes. Locoregional recurrence rates after surgery ranged from 15% to 52% over 3-5 years. Five-year overall survival rates varied from 22% to 53%. Surgeons should consider serum biomarkers like CEA and CA19-9, linked to poor survival, for patient risk assessment. Elevated CEA was associated with shorter overall survival in 11 studies. Contemporary biomarkers remain unstudied in this population, indicating a… Read more: Biomarkers for Recurrent Rectal Cancer Outcomes

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