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TOP STITCHES

  • New Immune Signatures in MEN1-Related Tumors
    Identifying immune signatures could refine patient selection and surgical outcomes for those with MEN1-related neuroendocrine tumors. Analyzed 42 MEN1 patients with duodenopancreatic neuroendocrine tumors (DPNETs); 14 had liver metastasis. Identified 1,117 immunoglobulin-bound proteins; 435 antigens enriched in DPNET patients, with 130 higher in those with liver metastasis. Surgeons may consider these findings for better risk stratification and individualized surgical approaches in treating MEN1. Networks indicated potential targets for immunotherapy based on B- and T-cell signaling pathways. Journal Article by Katayama… Read more: New Immune Signatures in MEN1-Related Tumors

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